Many neurological diseases are marked by a process of white matter neurodegeneration; that is, a breakdown of specific brain tissue involved in higher-order cognitive function. The global rise of dementia and Alzheimer’s disease is of urgent focus, but better medical diagnostic systems also offer epilepsy and multiple sclerosis patients hope. Since August 2009 Vasiliki Ikonomidou’s research conducted at Mason’s Krasnow Institute for Advanced Studies has been focused on improving MRI technologies to detect this unique and difficult to measure symptom. Iknomidou, an assistant professor in electrical and computer engineering, researches the development of multispectral and fusion image processing techniques for MRI. Prior to joining the faculty at Mason, she was part of the intramural program of the National Institutes of Health – National Institute of Neurological Disorders and Stroke and a visiting fellow in the Laboratory for Functional and Molecular Imaging, Advanced MRI Section, working und Dr. Jeff Guyn in the development of high-contrast anatomical MRI techniques. Ikonomidou shares her expansive knowledge of medical image processing and biomedical systems and signals to a variety of advanced undergraduate courses in electrical and computer engineering.